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Symbol Name ID |
Notch1
notch 1 MGI:97363 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Mouse Phenotypes | abnormal exocrine pancreas morphology |
abnormal pancreatic duct morphology |
endocrine/exocrine gland phenotype |
abnormal endocrine pancreas morphology |
abnormal pancreatic islet morphology |
decreased pancreatic alpha cell number |
absent pancreatic alpha cells |
decreased pancreatic beta cell number |
absent pancreatic islets |
abnormal thymus morphology |
abnormal thymus cell ratio |
small thymus |
thymus hypoplasia |
decreased thymocyte number |
Meibomian gland degeneration |
small sebaceous gland |
lacrimal gland degeneration |
abnormal pancreas development |
abnormal pancreas morphology |
increased T cell derived lymphoma incidence |
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| Availability | Mouse Genotype | ||||||||||||||||||||
| Notch1tm2Pst/Notch1tm2Pst | |||||||||||||||||||||
| Tg(LckNotch1)9Erob/? | |||||||||||||||||||||
| Notch1tm1Agt/Notch1tm1Agt Tg(Mx1-cre)1Cgn/0 (conditional) |
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| Cpa3tm3(icre)Hrr/Cpa3+ Notch1tm1Agt/Notch1tm1Agt (conditional) |
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| Notch1tm2Rko/Notch1tm2Rko Tg(Msx2-cre)5Rem/0 (conditional) |
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| Notch1tm2Rko/Notch1tm2Rko Tg(KRT14-rtTA)F42Efu/0 Tg(tetO-cre)1Jaw/0 (conditional) |
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| Gt(ROSA)26Sortm1(Notch1)Dam/Gt(ROSA)26Sor+ Tg(Pdx1-cre)89.1Dam/0 (conditional) |
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| Gt(ROSA)26Sortm1(Notch1)Dam/Gt(ROSA)26Sor+ Tg(Pdx1-cre/Esr1*)35.10Dam/0 (conditional) |
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| Gt(ROSA)26Sortm1(Notch1)Dam/Gt(ROSA)26Sor+ Tg(Neurog3-cre/Esr1*)1Dam/0 (conditional) |
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| Gt(ROSA)26Sortm1(Notch1)Dam/Gt(ROSA)26Sor+ Hes1tm1(cre/ERT2)Lcm/Hes1+ (conditional) |
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| Gt(ROSA)26Sortm1(Notch1)Dam/Gt(ROSA)26Sor+ Tg(Neurog3-cre)C1Able/0 (conditional) |
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| Gt(ROSA)26Sortm1(Notch1)Dam/Gt(ROSA)26Sor+ Tg(Neurod1-cre)1Able/0 (conditional) |
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| Gt(ROSA)26Sortm1(Notch1)Dam/Gt(ROSA)26Sor+ Tg(Neurog3-cre/ERT2)1Able/0 (conditional) |
* | ||||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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